Sterols

NPC1 like intracellular cholesterol transporter 1 ; Homo sapiens







29 Article(s)
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1 31867479 Computational Modeling Explains the Multi Sterol Ligand Specificity of the N-Terminal Domain of Niemann-Pick C1-Like 1 Protein. 2019 Dec 17 6
2 29764733 Genetic polymorphism of sterol transporters in children with future gallstones. 2018 Sep 1
3 26923679 Niemann-Pick C1-Like 1 (NPC1L1) Inhibition and Cardiovascular Diseases. 2016 1
4 24906511 Structure-activity relationship study of non-steroidal NPC1L1 ligands identified through cell-based assay using pharmacological chaperone effect as a readout. 2014 Jul 15 1
5 22213168 Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease. 2012 May 2
6 23258338 [Progress of Niemann-Pick type C1 Like 1 on cholesterol metabolism]. 2012 Dec 25 1
7 21437027 Phytosterols and phytosterolemia: gene-diet interactions. 2011 Feb 2
8 21525977 The structure of the NPC1L1 N-terminal domain in a closed conformation. 2011 Apr 15 3
9 19747803 An NPC1L1 gene promoter variant is associated with autosomal dominant hypercholesterolemia. 2010 May 3
10 19907422 Transporters as drug targets: discovery and development of NPC1L1 inhibitors. 2010 Jan 1
11 20307540 NPC1L1 and cholesterol transport. 2010 Jul 2 2
12 19122238 Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster. 2009 Jun 1
13 19963159 Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells. 2009 Dec 1
14 18460917 The structure and function of Niemann-Pick C1-like 1 protein. 2008 Jun 4
15 18496605 The role of Niemann-Pick C1 - Like 1 (NPC1L1) in intestinal sterol absorption. 2008 Apr 5
16 18522832 The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1. 2008 Jun 1
17 18523240 Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells. 2008 Sep 3
18 18591835 Ezetimibe, a selective inhibitor of the transport of cholesterol. 2008 2
19 18668442 Cholesterol and non-cholesterol sterol transporters: ABCG5, ABCG8 and NPC1L1: a review. 2008 Jul 1
20 18850127 Genetic variation in ABC G5/G8 and NPC1L1 impact cholesterol response to plant sterols in hypercholesterolemic men. 2008 Dec 2
21 20300301 Standardization of PCR-RFLP analysis of nsSNP rs1468384 of NPC1L1 gene. 2008 Sep 2
22 17008555 Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2. 2007 Jan 2
23 17135346 Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells. 2007 Feb 2
24 17473178 Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells. 2007 Aug 1
25 16410048 Plant sterols combined with exercise for the treatment of hypercholesterolemia: overview of independent and synergistic mechanisms of action. 2006 Apr 1
26 16449388 Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. 2006 Feb 7 1
27 16973966 NPC1L1: evolution from pharmacological target to physiological sterol transporter. 2006 Nov 2
28 15992510 Cholesterol and plant sterol absorption: recent insights. 2005 Jul 4 1
29 10783261 Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1. 2000 Apr 15 1