Sterols

farnesyl-diphosphate farnesyltransferase 1 ; Homo sapiens







20 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30578317 The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis. 2019 Jan 16 1
2 25093296 Directed evolution of squalene synthase for dehydrosqualene biosynthesis. 2014 Sep 17 1
3 22425978 Molecular cloning, bacterial expression and promoter analysis of squalene synthase from Withania somnifera (L.) Dunal. 2012 May 10 1
4 19194910 Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies. 2008 Sep-Oct 1
5 17483544 Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation. 2007 Jun 29 2
6 17709461 Quinuclidine derivatives as potential antiparasitics. 2007 Nov 2
7 16198340 Antiproliferative and ultrastructural effects of BPQ-OH, a specific inhibitor of squalene synthase, on Leishmania amazonensis. 2005 Dec 1
8 15215084 In vitro and in vivo activities of E5700 and ER-119884, two novel orally active squalene synthase inhibitors, against Trypanosoma cruzi. 2004 Jul 1
9 11008488 Squalene synthase: structure and regulation. 2001 6
10 10677224 Squalene synthase: steady-state, pre-steady-state, and isotope-trapping studies. 2000 Feb 22 1
11 11111077 Structure and regulation of mammalian squalene synthase. 2000 Dec 15 2
12 9989262 The physiological role of sterol regulatory element-binding protein-2 in cultured human cells. 1999 Jan 4 1
13 9514656 Compensatory responses to inhibition of hepatic squalene synthase. 1998 Mar 15 1
14 9604010 Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase. 1998 Jun 3
15 9624172 Differential roles of extracellular signal-regulated kinase-1/2 and p38(MAPK) in interleukin-1beta- and tumor necrosis factor-alpha-induced low density lipoprotein receptor expression in HepG2 cells. 1998 Jun 19 1
16 8704125 Molecular cloning, in vitro expression and characterization of a plant squalene synthetase cDNA. 1996 Mar 1
17 7721822 Inhibition of mammalian squalene synthetase activity by zaragozic acid A is a result of competitive inhibition followed by mechanism-based irreversible inactivation. 1995 Apr 21 2
18 8020937 Localization of the squalene synthase gene (FDFT1) to human chromosome 8p22-p23.1. 1994 Mar 1 1
19 8474436 Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation. 1993 May 2
20 2538145 Regulation of squalene synthetase in human hepatoma cell line Hep G2 by sterols, and not by mevalonate-derived non-sterols. 1989 Mar 14 2