Protein Name component of oligomeric golgi complex 2
Organism Homo sapiens
Gene ID 22796
Gene Symbol

COG2

UniProt Q14746 (COG2_HUMAN), B1ALW7 (B1ALW7_HUMAN)
Relationships Total Number of functionally related compound(s) : 427
Total Number of Articles : 1370
Description

component of oligomeric golgi complex 2

Gene Summary

This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]

synonyms
  • conserved oligomeric Golgi complex subunit 2
  • COG complex subunit 2
  • brefeldin A-sensitive, peripheral Golgi protein
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Properties