lorlatinib


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61 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 173
2 ROS proto-oncogene 1, receptor tyrosine kinase ROS1_HUMAN ROS1 Homo sapiens 6098 101 63
3 anaplastic lymphoma kinase ALK_MOUSE Alk Mus musculus 11682 127 10
4 EMAP like 4 EMAL4_HUMAN EML4 Homo sapiens 27436 62 8
5 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 7
6 CD74 molecule HG2A_HUMAN CD74 Homo sapiens 972 80 3
7 Ros1 proto-oncogene ROS1_MOUSE Ros1 Mus musculus 19886 18 3
8 leukocyte receptor tyrosine kinase LTK_HUMAN LTK Homo sapiens 4058 45 2
9 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 2
10 cytochrome P450, family 3, subfamily a, polypeptide 11 CP3AB_MOUSE Cyp3a11 Mus musculus 13112 336 2
11 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 2
12 CEA cell adhesion molecule 3 CEAM3_HUMAN CEACAM3 Homo sapiens 1084 1053 2
13 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2
14 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 2
15 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 2
16 CAP-Gly domain containing linker protein 1 CLIP1_HUMAN CLIP1 Homo sapiens 6249 141 2
17 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 1
18 matrix metallopeptidase 7 MMP7_HUMAN MMP7 Homo sapiens 4316 380 1
19 secreted phosphoprotein 1 OSTP_MOUSE Spp1 Mus musculus 20750 432 1
20 immunoglobulin kappa variable 2-28 - IGKV2-28 Homo sapiens 28921 36 1
21 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 1
22 transforming growth factor alpha TGFA_MOUSE Tgfa Mus musculus 21802 542 1
23 FER tyrosine kinase FER_HUMAN FER Homo sapiens 2241 53 1
24 ALK receptor tyrosine kinase - ALK Bos taurus 536642 5 1
25 neurofibromin 1 NF1_MOUSE Nf1 Mus musculus 18015 138 1
26 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) HG2A_MOUSE Cd74 Mus musculus 16149 30 1
27 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 1
28 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 1
29 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 1
30 nuclear receptor subfamily 1 group I member 2 NR1I2_HUMAN NR1I2 Homo sapiens 8856 820 1
31 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
32 SAFB like transcription modulator SLTM_HUMAN SLTM Homo sapiens 79811 394 1
33 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 1
34 BCL2 like 11 B2L11_HUMAN BCL2L11 Homo sapiens 10018 399 1
35 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 1
36 solute carrier family 29 member 2 S29A2_HUMAN SLC29A2 Homo sapiens 3177 143 1
37 erb-b2 receptor tyrosine kinase 4 ERBB4_MOUSE Erbb4 Mus musculus 13869 71 1
38 tropomyosin 4 TPM4_HUMAN TPM4 Homo sapiens 7171 6 1
39 CAP-GLY domain containing linker protein 1 CLIP1_MOUSE Clip1 Mus musculus 56430 6 1
40 ezrin EZRI_MOUSE Ezr Mus musculus 22350 51 1
41 TOG array regulator of axonemal microtubules 2 TGRM2_HUMAN TOGARAM2 Homo sapiens 165186 1 1
42 PPFIA binding protein 1 LIPB1_HUMAN PPFIBP1 Homo sapiens 8496 2 1
43 EMAP like 4 F1N1R8_BOVIN EML4 Bos taurus 540187 2 1
44 Rho GTPase activating protein 23 RHG23_HUMAN ARHGAP23 Homo sapiens 57636 1 1
45 proline rich coiled-coil 2B PRC2B_HUMAN PRRC2B Homo sapiens 84726 4 1
46 solute carrier family 29 member 1 (Augustine blood group) S29A1_HUMAN SLC29A1 Homo sapiens 2030 348 1
47 fibronectin 1 FINC_HUMAN FN1 Homo sapiens 2335 2017 1
48 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 1
49 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 1
50 vimentin VIME_HUMAN VIM Homo sapiens 7431 1102 1