FOLFIRI regimen


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62 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 31
2 UDP glucuronosyltransferase family 1 member A1 UD11_HUMAN UGT1A1 Homo sapiens 54658 747 20
3 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 13
4 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 9
5 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 9
6 NRAS proto-oncogene, GTPase RASN_HUMAN NRAS Homo sapiens 4893 357 5
7 CEA cell adhesion molecule 3 CEAM3_HUMAN CEACAM3 Homo sapiens 1084 1053 5
8 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 3
9 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 2
10 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 2
11 metallothionein 1E MT1E_HUMAN MT1E Homo sapiens 4493 133 2
12 carcinoembryonic antigen gene family - Cea Mus musculus 111518 172 1
13 MAX dimerization protein MGA MGAP_HUMAN MGA Homo sapiens 23269 43 1
14 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 1
15 ATP binding cassette subfamily B member 6 (Langereis blood group) ABCB6_HUMAN ABCB6 Homo sapiens 10058 793 1
16 Moloney sarcoma oncogene MOS_MOUSE Mos Mus musculus 17451 147 1
17 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 1
18 cyclin dependent kinase inhibitor 2A ARF_HUMAN CDKN2A Homo sapiens 1029 859 1
19 Fas ligand TNFL6_HUMAN FASLG Homo sapiens 356 783 1
20 APC regulator of WNT signaling pathway APC_HUMAN APC Homo sapiens 324 385 1
21 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 1
22 X-linked Kx blood group XK_HUMAN XK Homo sapiens 7504 753 1
23 BCAR1 scaffold protein, Cas family member BCAR1_HUMAN BCAR1 Homo sapiens 9564 545 1
24 proteasome 26S subunit, non-ATPase 1 PSMD1_HUMAN PSMD1 Homo sapiens 5707 302 1
25 placental growth factor PLGF_HUMAN PGF Homo sapiens 5228 355 1
26 amphiregulin AREG_HUMAN AREG Homo sapiens 374 200 1
27 serine hydroxymethyltransferase 1 GLYC_HUMAN SHMT1 Homo sapiens 6470 126 1
28 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 1
29 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 1
30 UDP glucuronosyltransferase family 1 member A complex locus - UGT1A Homo sapiens 7361 716 1
31 toll like receptor 1 TLR1_HUMAN TLR1 Homo sapiens 7096 148 1
32 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 1
33 protein kinase AMP-activated catalytic subunit alpha 1 AAPK1_HUMAN PRKAA1 Homo sapiens 5562 812 1
34 interleukin 15 receptor subunit alpha I15RA_HUMAN IL15RA Homo sapiens 3601 28 1
35 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 1
36 ATP binding cassette subfamily C member 2 MRP2_HUMAN ABCC2 Homo sapiens 1244 684 1
37 SMAD family member 3 SMAD3_HUMAN SMAD3 Homo sapiens 4088 464 1
38 PIN2 (TERF1) interacting telomerase inhibitor 1 PINX1_HUMAN PINX1 Homo sapiens 54984 37 1
39 EPH receptor A2 EPHA2_HUMAN EPHA2 Homo sapiens 1969 198 1
40 serine/threonine kinase 11 STK11_HUMAN STK11 Homo sapiens 6794 365 1
41 R-spondin 2 RSPO2_HUMAN RSPO2 Homo sapiens 340419 19 1
42 C-X-C motif chemokine ligand 5 CXCL5_HUMAN CXCL5 Homo sapiens 6374 126 1
43 ubiquitin like 5 UBL5_HUMAN UBL5 Homo sapiens 59286 75 1
44 mitogen-activated protein kinase kinase kinase 7 M3K7_HUMAN MAP3K7 Homo sapiens 6885 250 1
45 Fc gamma receptor IIa FCG2A_HUMAN FCGR2A Homo sapiens 2212 169 1
46 MAPK interacting serine/threonine kinase 1 MKNK1_HUMAN MKNK1 Homo sapiens 8569 92 1
47 RB1 inducible coiled-coil 1 RBCC1_HUMAN RB1CC1 Homo sapiens 9821 34 1
48 galanin receptor 2 GALR2_HUMAN GALR2 Homo sapiens 8811 37 1
49 glutathione peroxidase 7 GPX7_HUMAN GPX7 Homo sapiens 2882 34 1
50 timeless circadian regulator TIM_HUMAN TIMELESS Homo sapiens 8914 36 1