| 1 |
35204767 | 6-Hydroxydopamine Induces Abnormal Iron Sequestration in BV2 Microglia by Activating Iron Regulatory Protein 1 and Inhibiting Hepcidin Release. | 2022 Feb 7 |
6 |
| 2 |
34870866 | Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron-induced hepatotoxicity. | 2021 Dec 6 |
1 |
| 3 |
31661462 | Effects of maternal iron status on placental and fetal iron homeostasis. | 2020 Feb 3 |
2 |
| 4 |
31697569 | Long Noncoding RNA FENDRR Exhibits Antifibrotic Activity in Pulmonary Fibrosis. | 2020 Apr |
1 |
| 5 |
31883180 | Soluble iron accumulation induces microglial glutamate release in the spinal cord of sporadic amyotrophic lateral sclerosis. | 2020 Apr |
1 |
| 6 |
29746238 | Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism. | 2018 |
4 |
| 7 |
30002810 | Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease. | 2018 |
4 |
| 8 |
27545647 | Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure. | 2017 Feb 1 |
1 |
| 9 |
28542246 | A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat. | 2017 |
4 |
| 10 |
25651183 | Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency. | 2015 Feb 3 |
8 |
| 11 |
25771171 | Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins. | 2015 Sep |
7 |
| 12 |
24982634 | The physiological functions of iron regulatory proteins in iron homeostasis - an update. | 2014 |
3 |
| 13 |
25120486 | The IRP/IRE system in vivo: insights from mouse models. | 2014 |
3 |
| 14 |
23376588 | Pro-inflammatory cytokines modulate iron regulatory protein 1 expression and iron transportation through reactive oxygen/nitrogen species production in ventral mesencephalic neurons. | 2013 May |
1 |
| 15 |
23395173 | Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. | 2013 Feb 5 |
1 |
| 16 |
23395174 | The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption. | 2013 Feb 5 |
3 |
| 17 |
23455710 | Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function. | 2013 Jul |
6 |
| 18 |
23777768 | IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation. | 2013 Aug 29 |
5 |
| 19 |
24146952 | Iron accumulates in Huntington's disease neurons: protection by deferoxamine. | 2013 |
4 |
| 20 |
22435664 | Alterations in renal iron metabolism caused by a copper/zinc-superoxide dismutase deficiency. | 2012 Jun |
1 |
| 21 |
21566147 | Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide. | 2011 Jul 1 |
9 |
| 22 |
21884746 | Identification of a new protective antigen of Bordetella pertussis. | 2011 Nov 3 |
2 |
| 23 |
19533074 | In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation. | 2009 Sep |
1 |
| 24 |
18685102 | Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice. | 2008 Aug 19 |
9 |
| 25 |
17560557 | Regional dissection and determination of loosely bound and non-heme iron in the developing mouse brain. | 2007 Jul 16 |
3 |
| 26 |
17614197 | Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice. | 2007 Jul 18 |
1 |
| 27 |
16424901 | Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster. | 2006 Feb 8 |
8 |
| 28 |
16467350 | The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. | 2006 Mar 15 |
2 |
| 29 |
16770644 | IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice. | 2006 Jul |
1 |
| 30 |
16886906 | STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide. | 2006 Dec 1 |
1 |
| 31 |
15557328 | Down-regulation of iron regulatory protein 1 activities and expression in superoxide dismutase 1 knock-out mice is not associated with alterations in iron metabolism. | 2005 Feb 11 |
2 |
| 32 |
15629469 | Induction of iron regulatory protein 1 RNA-binding activity by nitric oxide is associated with a concomitant increase in the labile iron pool: implications for DNA damage. | 2005 Feb 4 |
5 |
| 33 |
15664434 | Different cytoprotective effect of antioxidants and change in the iron regulatory system in rodent cells exposed to paraquat or formaldehyde. | 2005 Mar 1 |
1 |
| 34 |
15710243 | Changed iron regulation in scrapie-infected neuroblastoma cells. | 2005 Feb 18 |
8 |
| 35 |
16051392 | Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice. | 2005 Oct 3 |
2 |
| 36 |
16283625 | Generation of conditional alleles of the murine Iron Regulatory Protein (IRP)-1 and -2 genes. | 2005 Dec |
1 |
| 37 |
14726953 | Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis. | 2004 Jan 28 |
3 |
| 38 |
15105256 | Severity of neurodegeneration correlates with compromise of iron metabolism in mice with iron regulatory protein deficiencies. | 2004 Mar |
1 |
| 39 |
15258160 | Endogenous nitration of iron regulatory protein-1 (IRP-1) in nitric oxide-producing murine macrophages: further insight into the mechanism of nitration in vivo and its impact on IRP-1 functions. | 2004 Oct 8 |
5 |
| 40 |
12572672 | Role of nitric oxide in cellular iron metabolism. | 2003 Mar |
2 |
| 41 |
12946050 | What have we learnt from CDNA microarray gene expression studies about the role of iron in MPTP induced neurodegeneration and Parkinson's disease? | 2003 |
4 |
| 42 |
12044177 | Nitric oxide and peroxynitrite activate the iron regulatory protein-1 of J774A.1 macrophages by direct disassembly of the Fe-S cluster of cytoplasmic aconitase. | 2002 Jun 11 |
16 |
| 43 |
12124425 | An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells. | 2002 Jul |
4 |
| 44 |
12209009 | Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis. | 2002 Sep 17 |
1 |
| 45 |
12547230 | Nitric oxide-mediated modulation of iron regulatory proteins: implication for cellular iron homeostasis. | 2002 Nov-Dec |
2 |
| 46 |
11175792 | Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. | 2001 Feb |
1 |
| 47 |
11264285 | Modulation of cellular iron metabolism by hydrogen peroxide. Effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. | 2001 Jun 8 |
3 |
| 48 |
11341946 | Effects of hyperoxia and iron on iron regulatory protein-1 activity and the ferritin synthesis in mouse peritoneal macrophages. | 2001 Jan 12 |
7 |
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10692416 | Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2. | 2000 Mar 3 |
1 |
| 50 |
10704227 | Nitrogen monoxide activates iron regulatory protein 1 RNA-binding activity by two possible mechanisms: effect on the [4Fe-4S] cluster and iron mobilization from cells. | 2000 Mar 14 |
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