Pub. Date : 2004 Jan 28
PMID : 14726953
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The two iron regulatory proteins IRP1 and IRP2 bind to transcripts of ferritin, transferrin receptor and other target genes to control the expression of iron metabolism proteins at the post-transcriptional level. | Iron | aconitase 1 | Mus musculus |
2 | The two iron regulatory proteins IRP1 and IRP2 bind to transcripts of ferritin, transferrin receptor and other target genes to control the expression of iron metabolism proteins at the post-transcriptional level. | Iron | aconitase 1 | Mus musculus |
3 | IRP1-/- mice misregulate iron metabolism only in the kidney and brown fat, two tissues in which the endogenous expression level of IRP1 greatly exceeds that of IRP2, whereas IRP2-/- mice misregulate the expression of target proteins in all tissues. | Iron | aconitase 1 | Mus musculus |