Pub. Date : 2002 Jul
PMID : 12124425
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In contrast, IRP1 activity decreased when iron increased up to 20 microm, and then, unexpectedly, increased. | Iron | aconitase 1 | Mus musculus |
| 2 | IRP1 activity at iron concentrations above 20 microm was functional as it correlated with increased (55) Fe uptake. | Iron | aconitase 1 | Mus musculus |
| 3 | IRP1 activity at iron concentrations above 20 microm was functional as it correlated with increased (55) Fe uptake. | Iron | aconitase 1 | Mus musculus |
| 4 | This behavior is probably a consequence of the paradoxical activation of IRP1 at high iron concentrations, a condition that may underlie some processes associated with neuronal degeneration and death. | Iron | aconitase 1 | Mus musculus |