Pub. Date : 2013 Jul
PMID : 23455710
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function. | Iron | aconitase 1 | Mus musculus |
| 2 | Cellular iron homeostasis is maintained by iron regulatory proteins (IRP)-1 and 2 through their binding to cis-regulatory iron-responsive elements (IREs) in target mRNAs. | Iron | aconitase 1 | Mus musculus |
| 3 | Cellular iron homeostasis is maintained by iron regulatory proteins (IRP)-1 and 2 through their binding to cis-regulatory iron-responsive elements (IREs) in target mRNAs. | Iron | aconitase 1 | Mus musculus |
| 4 | Cellular iron homeostasis is maintained by iron regulatory proteins (IRP)-1 and 2 through their binding to cis-regulatory iron-responsive elements (IREs) in target mRNAs. | Iron | aconitase 1 | Mus musculus |
| 5 | IRP1 activation alters the expression of IRP target genes and is accompanied by iron loading in the same organs. | Iron | aconitase 1 | Mus musculus |
| 6 | Thus, inappropriately high IRP1 activity causes disturbed body iron distribution and erythropoiesis. | Iron | aconitase 1 | Mus musculus |