Title : STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide.

Pub. Date : 2006 Dec 1

PMID : 16886906






1 Functional Relationships(s)
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1 Analysis of the mouse IRP1 promoter sequence revealed two conserved putative binding sites for transcription factor(s) regulated by NO and/or changes in intracellular iron level: Sp1 (promoter-selective transcription factor 1) and MTF1 (metal transcription factor 1), plus GAS (interferon-gamma-activated sequence), a binding site for STAT (signal transducer and activator of transcription) proteins. Iron aconitase 1 Mus musculus