Title : Role of nitric oxide in cellular iron metabolism.

Pub. Date : 2003 Mar

PMID : 12572672






2 Functional Relationships(s)
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1 Moreover, NO*, a redox species of nitric oxide that interacts primarily with iron, can activate IRP1 RNA-binding activity resulting in an increase in TfR mRNA levels. Iron aconitase 1 Mus musculus
2 Iron regulatory proteins (IRP1 and IRP2) control the synthesis of transferrin receptors (TfR) and ferritin by binding to iron-responsive elements (IREs) which are located in the 3" untranslated region (UTR) and the 5" UTR of their respective mRNAs. Iron aconitase 1 Mus musculus