Tyrosine

signal transducer and activator of transcription 1 ; Homo sapiens







438 Article(s)
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1 34310951 CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3. 2022 Feb 1
2 35016033 Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses. 2022 Feb 3 1
3 35085949 Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR. 2022 Mar 1
4 33472080 Critical role of Syk-dependent STAT1 activation in innate antiviral immunity. 2021 Jan 19 1
5 33815425 Monocytes From Patients With Macrophage Activation Syndrome and Secondary Hemophagocytic Lymphohistiocytosis Are Hyperresponsive to Interferon Gamma. 2021 1
6 34000478 STAT1 N-terminal domain discriminatively controls type I and type II IFN signaling. 2021 Aug 2
7 34023736 Cyclic mimetics of kinase-inhibitory region of Suppressors of Cytokine Signaling 1: Progress toward novel anti-inflammatory therapeutics. 2021 Oct 5 1
8 34303919 Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK. 2021 Sep 1
9 34319780 Suppression of JAK-STAT Signaling by Epstein-Barr Virus Tegument Protein BGLF2 through Recruitment of SHP1 Phosphatase and Promotion of STAT2 Degradation. 2021 Sep 27 1
10 34570089 Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells. 2021 Sep 9 1
11 31634391 All-trans Retinoic Acid Counteracts Diarrhea and Inhibition of Downregulated in Adenoma Expression in Gut Inflammation. 2020 Mar 4 1
12 31948748 STAT1 upregulates glutaminase and modulates amino acids and glutathione metabolism. 2020 Mar 12 1
13 32093058 Cytokine-Induced Guanylate Binding Protein 1 (GBP1) Release from Human Ovarian Cancer Cells. 2020 Feb 19 1
14 32295912 Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways. 2020 Jun 16 1
15 32420725 IL-1β Enhances the Antiviral Effect of IFN-α on HCV Replication by Negatively Modulating ERK2 Activation. 2020 Jul 10 2
16 32683298 Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1. 2020 Oct 2
17 32864202 Off-target effects of protein tyrosine phosphatase inhibitors on oncostatin M-treated human epidermal keratinocytes: the phosphatase targeting STAT1 remains unknown. 2020 2
18 33328346 Interactions of the Nipah Virus P, V, and W Proteins across the STAT Family of Transcription Factors. 2020 Dec 16 1
19 30804043 TLR-Induced IL-12 and CCL2 Production by Myeloid Cells Is Dependent on Adenosine A3 Receptor-Mediated Signaling. 2019 Apr 15 1
20 31221825 T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide. 2019 Aug 1
21 31228268 Phosphorylation of STAT1 serine 727 enhances platinum resistance in uterine serous carcinoma. 2019 Sep 15 1
22 31248982 Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling. 2019 Aug 16 1
23 31605752 LncRNA625 inhibits STAT1-mediated transactivation potential in esophageal cancer cells. 2019 Dec 1
24 31846457 The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis. 2019 1
25 28736298 Calcitriol-mediated reduction in IFN-γ output in T cell large granular lymphocytic leukemia requires vitamin D receptor upregulation. 2018 Mar 3
26 29394132 Decrease in invasion of HTR-8/SVneo trophoblastic cells by interferon gamma involves cross-communication of STAT1 and BATF2 that regulates the expression of JUN. 2018 1
27 29474442 Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia. 2018 2
28 29796172 Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies. 2018 May 1 2
29 29859868 Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events. 2018 Sep 1
30 30007645 Discovery of a polysaccharide from the fruiting bodies of Lepista sordida as potent inhibitors of indoleamine 2, 3-dioxygenase (IDO) in HepG2 cells via blocking of STAT1-mediated JAK-PKC-δ signaling pathways. 2018 Oct 1 1
31 30455079 Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes. 2018 Nov 1
32 30588194 Cancer/testis Antigen MAGEA3 Interacts with STAT1 and Remodels the Tumor Microenvironment. 2018 3
33 27862996 Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells. 2017 Apr 1
34 28086195 Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms. 2017 Apr 2
35 28174303 Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses. 2017 Mar 17 1
36 28427901 The 20kDa and 22kDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties. 2017 Jul 1 1
37 28542650 Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion. 2017 2
38 28914637 Signal transducer and activator of transcription gain-of-function primary immunodeficiency/immunodysregulation disorders. 2017 Dec 1
39 29239838 Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation. 2017 Dec 1
40 26265185 HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia. 2016 Jan 1
41 27137788 Cystatin B and HIV regulate the STAT-1 signaling circuit in HIV-infected and INF-β-treated human macrophages. 2016 Oct 2
42 27434509 Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus. 2016 Jul 3
43 26141950 STAT1 Activation Is Enhanced by Cisplatin and Variably Affected by EGFR Inhibition in HNSCC Cells. 2015 Sep 1
44 26232434 Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1. 2015 Sep 15 3
45 26275341 The two interfaces of the STAT1 N-terminus exhibit opposite functions in IFNγ-regulated gene expression. 2015 Oct 2
46 26339056 Structural Basis of the Inhibition of STAT1 Activity by Sendai Virus C Protein. 2015 Nov 5
47 26553978 Mutations in the linker domain affect phospho-STAT3 function and suggest targets for interrupting STAT3 activity. 2015 Dec 1 2
48 26719274 Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation. 2015 Dec 30 1
49 24131713 Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activation. 2014 Jan 1
50 24319264 "Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells. 2014 Jan 1 2