Title : Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.

Pub. Date : 2017 Mar 17

PMID : 28174303






1 Functional Relationships(s)
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1 Interestingly, IFNgamma-induced tyrosine phosphorylation of STAT1 is reduced in cells with targeted disruption of Sin1, leading to decreased transcription of several IFNgamma-inducible genes in an mTORC2-independent manner. Tyrosine signal transducer and activator of transcription 1 Homo sapiens