Title : Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling.

Pub. Date : 2019 Aug 16

PMID : 31248982

1 Functional Relationships(s)
Compound Name
Protein Name
1 Accordingly, cell experiments revealed that 1,4-benzoquinone exposure irreversibly inhibits cellular PTPN2 and concomitantly increases tyrosine phosphorylation of STAT1 and expression of STAT1-regulated genes. Tyrosine signal transducer and activator of transcription 1 Homo sapiens