Title : The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis.

Pub. Date : 2019

PMID : 31846457






1 Functional Relationships(s)
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1 To this purpose, the mRNA expression levels of IFNG and IFNgamma-inducible genes as well as Tyrosine (701)-phosphorylated signal transducer and activator of transcription 1 (STAT1) protein levels were evaluated in the liver and in peripheral blood mononuclear cells (PBMCs) of three patients with sHLH with predominant liver involvement. Tyrosine signal transducer and activator of transcription 1 Homo sapiens