Title : Critical role of Syk-dependent STAT1 activation in innate antiviral immunity.

Pub. Date : 2021 Jan 19

PMID : 33472080






1 Functional Relationships(s)
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1 Syk deletion profoundly impairs immediate innate immunity, as evidenced by the finding that Syk deletion attenuates tyrosine phosphorylation of STAT1 and reduces the expressions of interferon-stimulated genes (ISGs) in vitro and in vivo. Tyrosine signal transducer and activator of transcription 1 Homo sapiens