Title : T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide.

Pub. Date : 2019 Aug

PMID : 31221825






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Exposure of human hematopoietic cells (HL60 and Jurkat) to EQ led to inhibition of endogenous TCPTP and concomitant increase in STAT1 tyrosine phosphorylation. Tyrosine signal transducer and activator of transcription 1 Homo sapiens