Title : "Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells.

Pub. Date : 2014 Jan 1

PMID : 24319264






2 Functional Relationships(s)
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1 We conclude that the inhibition of canonical STAT1 and STAT3 target gene expression abrogates their intrinsic negative feedback loops, leading to accumulation of phospho-tyrosine-STAT3 and prolonged STAT1 phosphorylation. Tyrosine signal transducer and activator of transcription 1 Homo sapiens
2 We conclude that the inhibition of canonical STAT1 and STAT3 target gene expression abrogates their intrinsic negative feedback loops, leading to accumulation of phospho-tyrosine-STAT3 and prolonged STAT1 phosphorylation. Tyrosine signal transducer and activator of transcription 1 Homo sapiens