Title : STAT1 Activation Is Enhanced by Cisplatin and Variably Affected by EGFR Inhibition in HNSCC Cells.

Pub. Date : 2015 Sep

PMID : 26141950






1 Functional Relationships(s)
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1 Using in vitro studies, we tested the hypothesis that cisplatin and EGFR inhibitors rely on the activation of the tumor suppressor STAT1, characterized by its phosphorylation at serine (S727) or tyrosine (Y701) residues. Tyrosine signal transducer and activator of transcription 1 Homo sapiens