51 | 7736912 | Inactivation of constitutive hepatic cytochromes P450 by phencyclidine in the rat. | Drug Metab Dispos | 1995 Feb |
1 |
52 | 7835216 | 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) modulates rat liver microsomal cyclophosphamide and ifosphamide activation by suppressing cytochrome P450 2C11 messenger RNA levels. | Drug Metab Dispos | 1994 Sep-Oct |
3 |
53 | 7838134 | Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism? | Mol Pharmacol | 1995 Jan |
4 |
54 | 7839362 | Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation. | Toxicol Appl Pharmacol | 1995 Jan |
1 |
55 | 7890112 | Induction of cytochrome P450 by toluene. | Int J Biochem | 1994 Dec |
1 |
56 | 7918645 | Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver. | Biochim Biophys Acta | 1994 Oct 18 |
1 |
57 | 7932191 | Selective suppression of rat hepatic cytochrome P450 2C11 by chloramphenicol. | J Pharmacol Exp Ther | 1994 Sep |
1 |
58 | 7956732 | Evidence that the biotransformation of dapsone and monoacetyldapsone to their respective hydroxylamine metabolites in rat liver microsomes is mediated by cytochrome P450 2C6/2C11 and 3A1. | Drug Metab Dispos | 1994 Jul-Aug |
1 |
59 | 7965769 | Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate. | J Pharmacol Exp Ther | 1994 Nov |
1 |
60 | 7986207 | Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs). | Biochem Pharmacol | 1994 Nov 16 |
1 |
61 | 8080435 | CYP2C11 and CYP2B1 are major cytochrome P450 forms involved in styrene oxidation in liver and lung microsomes from untreated rats, respectively. | Biochem Pharmacol | 1994 Aug 17 |
10 |
62 | 8081427 | Expression of the CYP3A and CYP2C11 enzymes in a nutritionally obese rodent model: response to phenobarbital treatment. | Int J Obes Relat Metab Disord | 1994 Jun |
1 |
63 | 8104124 | Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation. | Drug Metab Dispos | 1993 Jul-Aug |
3 |
64 | 8274026 | Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment. | Arch Biochem Biophys | 1993 Dec |
7 |
65 | 8304968 | Trimethadione metabolism, a useful indicator for assessing hepatic drug-oxidizing capacity. | Biochem Pharmacol | 1994 Jan 20 |
4 |
66 | 8347164 | Monoclonal antibody-directed assessment of toluene induction of rat hepatic cytochrome P450 isozymes. | Biochem Pharmacol | 1993 Aug 3 |
2 |
67 | 8423543 | Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat. | J Pharmacol Exp Ther | 1993 Jan |
2 |
68 | 8423554 | Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A). | J Pharmacol Exp Ther | 1993 Jan |
5 |
69 | 8424823 | Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats. | Biochem Pharmacol | 1993 Jan 7 |
3 |
70 | 8424894 | The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver. | J Steroid Biochem Mol Biol | 1993 Jan |
1 |
71 | 8495410 | Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard. | Cancer Res | 1993 Jun 1 |
15 |
72 | 8496838 | Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate. | J Pharmacol Exp Ther | 1993 May |
1 |
73 | 8535396 | Cytochrome P450 isozymes involved in aromatic hydroxylation and side-chain N-desisopropylation of alprenolol in rat liver microsomes. | Biol Pharm Bull | 1995 Aug |
3 |
74 | 8573203 | Impact of tamoxifen on peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11, cytochrome P450 3A2, and steroid 5 alpha-reductase. | Biochem Pharmacol | 1996 Feb 9 |
3 |
75 | 8611037 | cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells. | Arch Biochem Biophys | 1996 Feb 15 |
7 |
76 | 8613933 | Phencyclidine metabolite irreversible binding in the rat: gonadal steroid regulation and CYP2C11. | J Pharmacol Exp Ther | 1996 Apr |
7 |
77 | 8619245 | Reproductive toxicity and growth effects in rats exposed to lead at different periods during development. | Toxicol Appl Pharmacol | 1996 Feb |
1 |
78 | 8620572 | Effect of exposure to four organic solvents on hepatic cytochrome P450 isozymes in rat. | Chem Biol Interact | 1996 Jan 5 |
2 |
79 | 8666339 | Persistent sex differences in growth control of early rat liver lesions are programmed during promotion in the resistant hepatocyte model. | Hepatology | 1996 Apr |
1 |
80 | 8678911 | Metabolite complex formation of orphenadrine with cytochrome P450. Involvement of CYP2C11 and CYP3A isozymes. | Biochem Pharmacol | 1996 Jul 12 |
2 |
81 | 8689952 | Effect of cimetidine on hepatic cytochrome P450: evidence for formation of a metabolite-intermediate complex. | Drug Metab Dispos | 1995 Dec |
2 |
82 | 8694846 | Effects of metyrapone on expression of CYPs 2C11, 3A2, and other 3A genes in rat hepatocytes cultured on matrigel. | Biochem Pharmacol | 1996 Jul 26 |
3 |
83 | 8736062 | Lack of effect of methotrexate on the expression of constitutive hepatic cytochromes P450 in the male rat. | Xenobiotica | 1996 May |
1 |
84 | 8743465 | Structure, regulation and physiological roles of urea transporters. | Kidney Int | 1996 Jun |
1 |
85 | 8781526 | Differential effects of neuroleptic agents on hepatic cytochrome P-450 isozymes in the male rat. | Biochim Biophys Acta | 1996 Aug 29 |
5 |
86 | 8801167 | Restoration of cytochrome P450 2C11 in vitamin A-deficient rat liver by exogenous androgen. | FASEB J | 1996 Jul |
4 |
87 | 8819526 | Peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase: pretranslational regulation and impact on microsomal drug activation. | J Pharmacol Exp Ther | 1996 Sep |
3 |
88 | 8823314 | Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera. | J Clin Invest | 1996 Sep 15 |
4 |
89 | 8889968 | Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis. | J Gastroenterol Hepatol | 1996 Sep |
2 |
90 | 8905915 | Regulation of constitutive rat hepatic cytochromes P450 by 3-methylcholanthrene. | Xenobiotica | 1996 Oct |
4 |
91 | 8924622 | Cytochrome P4502D and -2C enzymes catalyze the oxidative N-demethylation of the parkinsonism-inducing substance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rat liver microsomes. | Chem Res Toxicol | 1996 Jan-Feb |
1 |
92 | 8951224 | Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity. | Chem Res Toxicol | 1996 Dec |
2 |
93 | 8968370 | Enhanced inhibition of microsomal cytochrome P450 3A2 in rat liver during diltiazem biotransformation. | J Pharmacol Exp Ther | 1996 Dec |
1 |
94 | 9043798 | Water channels and urea transporters. | Clin Exp Pharmacol Physiol | 1997 Jan |
1 |
95 | 9067484 | Role of the aromatic hydrocarbon receptor in the suppression of cytochrome P-450 2C11 by polycyclic aromatic hydrocarbons. | Toxicol Lett | 1997 Feb 7 |
1 |
96 | 9076658 | Deamination of amphetamines by cytochromes P450: studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymes. | J Toxicol Sci | 1997 Feb |
4 |
97 | 9103546 | Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels. | J Pharmacol Exp Ther | 1997 Apr |
13 |
98 | 9149377 | Major role of the CYP2C isozymes in deamination of amphetamine and benzphetamine: evidence for the quinidine-specific inhibition of the reactions catalysed by rabbit enzyme. | Xenobiotica | 1997 Apr |
1 |
99 | 9176377 | Segmental localization of urea transporter mRNAs in rat kidney. | Am J Physiol | 1997 May |
1 |
100 | 9176742 | The role of different cytochrome P450 isoforms in in vitro chloroform metabolism. | J Biochem Toxicol | 1996 |
1 |