cytochrome P450, subfamily 2, polypeptide 11 ; Rattus norvegicus






417 Article(s)
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51 7736912 Inactivation of constitutive hepatic cytochromes P450 by phencyclidine in the rat. Drug Metab Dispos 1995 Feb 1
52 7835216 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) modulates rat liver microsomal cyclophosphamide and ifosphamide activation by suppressing cytochrome P450 2C11 messenger RNA levels. Drug Metab Dispos 1994 Sep-Oct 3
53 7838134 Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism? Mol Pharmacol 1995 Jan 4
54 7839362 Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation. Toxicol Appl Pharmacol 1995 Jan 1
55 7890112 Induction of cytochrome P450 by toluene. Int J Biochem 1994 Dec 1
56 7918645 Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver. Biochim Biophys Acta 1994 Oct 18 1
57 7932191 Selective suppression of rat hepatic cytochrome P450 2C11 by chloramphenicol. J Pharmacol Exp Ther 1994 Sep 1
58 7956732 Evidence that the biotransformation of dapsone and monoacetyldapsone to their respective hydroxylamine metabolites in rat liver microsomes is mediated by cytochrome P450 2C6/2C11 and 3A1. Drug Metab Dispos 1994 Jul-Aug 1
59 7965769 Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate. J Pharmacol Exp Ther 1994 Nov 1
60 7986207 Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs). Biochem Pharmacol 1994 Nov 16 1
61 8080435 CYP2C11 and CYP2B1 are major cytochrome P450 forms involved in styrene oxidation in liver and lung microsomes from untreated rats, respectively. Biochem Pharmacol 1994 Aug 17 10
62 8081427 Expression of the CYP3A and CYP2C11 enzymes in a nutritionally obese rodent model: response to phenobarbital treatment. Int J Obes Relat Metab Disord 1994 Jun 1
63 8104124 Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation. Drug Metab Dispos 1993 Jul-Aug 3
64 8274026 Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment. Arch Biochem Biophys 1993 Dec 7
65 8304968 Trimethadione metabolism, a useful indicator for assessing hepatic drug-oxidizing capacity. Biochem Pharmacol 1994 Jan 20 4
66 8347164 Monoclonal antibody-directed assessment of toluene induction of rat hepatic cytochrome P450 isozymes. Biochem Pharmacol 1993 Aug 3 2
67 8423543 Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat. J Pharmacol Exp Ther 1993 Jan 2
68 8423554 Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A). J Pharmacol Exp Ther 1993 Jan 5
69 8424823 Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats. Biochem Pharmacol 1993 Jan 7 3
70 8424894 The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver. J Steroid Biochem Mol Biol 1993 Jan 1
71 8495410 Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard. Cancer Res 1993 Jun 1 15
72 8496838 Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate. J Pharmacol Exp Ther 1993 May 1
73 8535396 Cytochrome P450 isozymes involved in aromatic hydroxylation and side-chain N-desisopropylation of alprenolol in rat liver microsomes. Biol Pharm Bull 1995 Aug 3
74 8573203 Impact of tamoxifen on peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11, cytochrome P450 3A2, and steroid 5 alpha-reductase. Biochem Pharmacol 1996 Feb 9 3
75 8611037 cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells. Arch Biochem Biophys 1996 Feb 15 7
76 8613933 Phencyclidine metabolite irreversible binding in the rat: gonadal steroid regulation and CYP2C11. J Pharmacol Exp Ther 1996 Apr 7
77 8619245 Reproductive toxicity and growth effects in rats exposed to lead at different periods during development. Toxicol Appl Pharmacol 1996 Feb 1
78 8620572 Effect of exposure to four organic solvents on hepatic cytochrome P450 isozymes in rat. Chem Biol Interact 1996 Jan 5 2
79 8666339 Persistent sex differences in growth control of early rat liver lesions are programmed during promotion in the resistant hepatocyte model. Hepatology 1996 Apr 1
80 8678911 Metabolite complex formation of orphenadrine with cytochrome P450. Involvement of CYP2C11 and CYP3A isozymes. Biochem Pharmacol 1996 Jul 12 2
81 8689952 Effect of cimetidine on hepatic cytochrome P450: evidence for formation of a metabolite-intermediate complex. Drug Metab Dispos 1995 Dec 2
82 8694846 Effects of metyrapone on expression of CYPs 2C11, 3A2, and other 3A genes in rat hepatocytes cultured on matrigel. Biochem Pharmacol 1996 Jul 26 3
83 8736062 Lack of effect of methotrexate on the expression of constitutive hepatic cytochromes P450 in the male rat. Xenobiotica 1996 May 1
84 8743465 Structure, regulation and physiological roles of urea transporters. Kidney Int 1996 Jun 1
85 8781526 Differential effects of neuroleptic agents on hepatic cytochrome P-450 isozymes in the male rat. Biochim Biophys Acta 1996 Aug 29 5
86 8801167 Restoration of cytochrome P450 2C11 in vitamin A-deficient rat liver by exogenous androgen. FASEB J 1996 Jul 4
87 8819526 Peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase: pretranslational regulation and impact on microsomal drug activation. J Pharmacol Exp Ther 1996 Sep 3
88 8823314 Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera. J Clin Invest 1996 Sep 15 4
89 8889968 Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis. J Gastroenterol Hepatol 1996 Sep 2
90 8905915 Regulation of constitutive rat hepatic cytochromes P450 by 3-methylcholanthrene. Xenobiotica 1996 Oct 4
91 8924622 Cytochrome P4502D and -2C enzymes catalyze the oxidative N-demethylation of the parkinsonism-inducing substance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rat liver microsomes. Chem Res Toxicol 1996 Jan-Feb 1
92 8951224 Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity. Chem Res Toxicol 1996 Dec 2
93 8968370 Enhanced inhibition of microsomal cytochrome P450 3A2 in rat liver during diltiazem biotransformation. J Pharmacol Exp Ther 1996 Dec 1
94 9043798 Water channels and urea transporters. Clin Exp Pharmacol Physiol 1997 Jan 1
95 9067484 Role of the aromatic hydrocarbon receptor in the suppression of cytochrome P-450 2C11 by polycyclic aromatic hydrocarbons. Toxicol Lett 1997 Feb 7 1
96 9076658 Deamination of amphetamines by cytochromes P450: studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymes. J Toxicol Sci 1997 Feb 4
97 9103546 Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels. J Pharmacol Exp Ther 1997 Apr 13
98 9149377 Major role of the CYP2C isozymes in deamination of amphetamine and benzphetamine: evidence for the quinidine-specific inhibition of the reactions catalysed by rabbit enzyme. Xenobiotica 1997 Apr 1
99 9176377 Segmental localization of urea transporter mRNAs in rat kidney. Am J Physiol 1997 May 1
100 9176742 The role of different cytochrome P450 isoforms in in vitro chloroform metabolism. J Biochem Toxicol 1996 1