Protein Name | cytochrome P450, subfamily 2, polypeptide 11 |
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Organism | Rattus norvegicus |
Gene ID | 29277 |
Gene Symbol | Cyp2c11 |
UniProt | P08683 (CP2CB_RAT), A0A0G2K879 (A0A0G2K879_RAT) |
Relationships |
Total Number of functionally related compound(s) :
427
Total Number of Articles : 417 |
Description |
cytochrome P450, subfamily 2, polypeptide 11 |
Gene Summary |
Enables arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; and testosterone 16-alpha-hydroxylase activity. Involved in epoxygenase P450 pathway and icosanoid biosynthetic process. Located in endoplasmic reticulum membrane. Biomarker of end stage renal disease; hypertension; and mental depression. Orthologous to human CYP2C18 (cytochrome P450 family 2 subfamily C member 18). [provided by Alliance of Genome Resources, Apr 2022] |
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Properties | |