Protein Name cytochrome P450, subfamily 2, polypeptide 11
Organism Rattus norvegicus
Gene ID 29277
Gene Symbol

Cyp2c11

UniProt P08683 (CP2CB_RAT), A0A0G2K879 (A0A0G2K879_RAT)
Relationships Total Number of functionally related compound(s) : 427
Total Number of Articles : 417
Description

cytochrome P450, subfamily 2, polypeptide 11

Gene Summary

Enables arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; and testosterone 16-alpha-hydroxylase activity. Involved in epoxygenase P450 pathway and icosanoid biosynthetic process. Located in endoplasmic reticulum membrane. Biomarker of end stage renal disease; hypertension; and mental depression. Orthologous to human CYP2C18 (cytochrome P450 family 2 subfamily C member 18). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytochrome P450 2C11
  • CYPIIC11
  • P-450(M-1)
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Properties