Title : The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver.

Pub. Date : 1993 Jan

PMID : 8424894






1 Functional Relationships(s)
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1 Anti-CYP3A4 antibody had no effect on that activity in fetal or in adult liver microsomes, whereas a monoclonal antibody 1-68-11 (generated against rat CYP2C11) slightly inhibited benzphetamine N-demethylase activity in adult liver. Benzphetamine cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus