| 101 |
26581908 | Anti-cancer effect of metformin by suppressing signaling pathway of HER2 and HER3 in tamoxifen-resistant breast cancer cells. | 2016 May |
2 |
| 102 |
26802022 | High efficacy of intravesical treatment of metformin on bladder cancer in preclinical model. | 2016 Feb 23 |
2 |
| 103 |
26892736 | The phenomenon of acquired resistance to metformin in breast cancer cells: The interaction of growth pathways and estrogen receptor signaling. | 2016 Apr |
1 |
| 104 |
26904687 | Metformin Synergistically Enhances Cisplatin-Induced Cytotoxicity in Esophageal Squamous Cancer Cells under Glucose-Deprivation Conditions. | 2016 |
1 |
| 105 |
27073554 | Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells. | 2016 Apr |
1 |
| 106 |
27378194 | Metformin use and gynecological cancers: A novel treatment option emerging from drug repositioning. | 2016 Sep |
1 |
| 107 |
27488947 | Metformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC. | 2016 Aug 4 |
1 |
| 108 |
25305450 | Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. | 2015 Jan 28 |
2 |
| 109 |
25542900 | Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin. | 2015 Mar 1 |
1 |
| 110 |
25598321 | β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1. | 2015 Mar |
2 |
| 111 |
25640355 | Metformin down-regulates endometrial carcinoma cell secretion of IGF-1 and expression of IGF-1R. | 2015 |
3 |
| 112 |
25780442 | Metformin inhibits the proliferation of A431 cells by modulating the PI3K/Akt signaling pathway. | 2015 Apr |
3 |
| 113 |
25790097 | IGF1 regulates PKM2 function through Akt phosphorylation. | 2015 |
1 |
| 114 |
25862373 | Metformin inhibits the proliferation of human prostate cancer PC-3 cells via the downregulation of insulin-like growth factor 1 receptor. | 2015 May 22 |
1 |
| 115 |
25879666 | Metformin suppresses diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-+Leprdb/+Leprdb mice. | 2015 |
1 |
| 116 |
25891779 | Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway. | 2015 Jun |
2 |
| 117 |
26045896 | Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action. | 2015 |
1 |
| 118 |
26050920 | The antitumor effect of metformin with and without carboplatin on primary endometrioid endometrial carcinoma in vivo. | 2015 Aug |
1 |
| 119 |
26052399 | Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin. | 2015 May 18 |
1 |
| 120 |
26101707 | Metformin inhibits gastric cancer via the inhibition of HIF1α/PKM2 signaling. | 2015 |
1 |
| 121 |
26111001 | Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth. | 2015 |
3 |
| 122 |
26291325 | Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions. | 2015 |
1 |
| 123 |
26312913 | A presurgical window-of-opportunity study of metformin in obesity-driven endometrial cancer. | 2015 Feb 26 |
1 |
| 124 |
26622608 | In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin. | 2015 Aug |
1 |
| 125 |
26665932 | [The effect of Metformin on the proliferation and collagen synthesis of human keloids fibroblasts]. | 2015 Jul |
1 |
| 126 |
24322659 | Metformin selectively targets tumor-initiating cells in ErbB2-overexpressing breast cancer models. | 2014 Feb |
1 |
| 127 |
24480115 | Metformin modulates PI3K and GLUT4 expression and Akt/PKB phosphorylation in human endometrial stromal cells after stimulation with androgen and insulin. | 2014 Apr |
5 |
| 128 |
24561578 | OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators. | 2014 May |
1 |
| 129 |
24750786 | Glioblastoma stem cells: a new target for metformin and arsenic trioxide. | 2014 Jan-Mar |
1 |
| 130 |
24858012 | Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells. | 2014 |
1 |
| 131 |
24903160 | Metformin prevents LYRM1-induced insulin resistance in 3T3-L1 adipocytes via a mitochondrial-dependent mechanism. | 2014 Dec |
1 |
| 132 |
24905037 | Therapeutic potential of metformin in papillary thyroid cancer in vitro and in vivo. | 2014 Aug 5 |
1 |
| 133 |
25013215 | Metformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indications. | 2014 Nov-Dec |
2 |
| 134 |
25120382 | Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA. | 2014 |
1 |
| 135 |
25122066 | Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer. | 2014 Oct |
1 |
| 136 |
25254953 | Mechanisms by which low glucose enhances the cytotoxicity of metformin to cancer cells both in vitro and in vivo. | 2014 |
1 |
| 137 |
25361177 | Metformin and erlotinib synergize to inhibit basal breast cancer. | 2014 Nov 15 |
1 |
| 138 |
25491250 | Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer. | 2014 |
2 |
| 139 |
25642303 | Evaluation of antagonistic effects of metformin with Cisplatin in gastric cancer cells. | 2014 Jul 1 |
2 |
| 140 |
23169238 | Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. | 2013 Feb 1 |
1 |
| 141 |
23255107 | Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt. | 2013 Jan 1 |
2 |
| 142 |
23437362 | Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells. | 2013 |
2 |
| 143 |
23568147 | Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells. | 2013 Nov |
6 |
| 144 |
23589723 | Activation of AMP-Activated Protein Kinase α and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells. | 2013 |
1 |
| 145 |
23663483 | Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells. | 2013 May 10 |
1 |
| 146 |
23879009 | [Metformin--new treatment strategies for gynecologic neoplasms]. | 2013 |
1 |
| 147 |
23904524 | Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment of adenomyosis. | 2013 Oct |
5 |
| 148 |
24009772 | Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts. | 2013 |
1 |
| 149 |
24403860 | Regulation of metformin response by breast cancer associated gene 2. | 2013 Dec |
3 |
| 150 |
22038047 | Caveolin-1 is essential for metformin inhibitory effect on IGF1 action in non-small-cell lung cancer cells. | 2012 Feb |
2 |