Pub. Date : 2016
PMID : 26904687
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The potential mechanisms underlying the synergistic effect of metformin on cisplatin-induced cytotoxicity under glucose-deprivation conditions may include enhancement of metformin-associated cytotoxicity, marked reduction in the cellular ATP levels, deregulation of the AKT and AMPK signaling pathways, and impaired DNA repair function. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |