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33126710 | Different Effects of Metformin and A769662 on Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells: Distinct Actions on Mitochondrial Fission and Respiration. | 2020 Oct 28 |
1 |
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30563932 | PRE-surgical Metformin In Uterine Malignancy (PREMIUM): a Multi-Center, Randomized Double-Blind, Placebo-Controlled Phase III Trial. | 2019 Apr 15 |
1 |
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30670777 | Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome. | 2019 May |
1 |
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30693913 | Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. | 2019 Jan 29 |
2 |
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30720062 | Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. | 2019 Apr |
2 |
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30816444 | MUL1 E3 ligase regulates the antitumor effects of metformin in chemoresistant ovarian cancer cells via AKT degradation. | 2019 May |
7 |
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30840303 | Metformin inhibits proliferation and migration of endometrial cancer cells through regulating PI3K/AKT/MDM2 pathway. | 2019 Feb |
3 |
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30911317 | Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells. | 2019 |
2 |
| 59 |
31028998 | Metformin inhibits the proliferation of rheumatoid arthritis fibroblast-like synoviocytes through IGF-IR/PI3K/AKT/m-TOR pathway. | 2019 Jul |
4 |
| 60 |
31082618 | Metformin inhibits β-catenin phosphorylation on Ser-552 through an AMPK/PI3K/Akt pathway in colorectal cancer cells. | 2019 Jul |
2 |
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31106005 | Metformin reverses PARP inhibitors-induced epithelial-mesenchymal transition and PD-L1 upregulation in triple-negative breast cancer. | 2019 |
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31607288 | [Effect of Metformin on Proliferation Capacity, Apoptosis and Glycolysis in K562 Cells]. | 2019 Oct |
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31870092 | Metformin Inhibit Cervical Cancer Migration by Suppressing the FAK/Akt Signaling Pathway. | 2019 Dec 1 |
3 |
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28696014 | Effect of metformin on ossification and inflammation of fibroblasts in ankylosing spondylitis: An in vitro study. | 2018 Jan |
1 |
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29086064 | Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells. | 2018 Jan |
1 |
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29117515 | Metformin and epothilone A treatment up regulate pro-apoptotic PARP-1, Casp-3 and H2AX genes and decrease of AKT kinase level to control cell death of human hepatocellular carcinoma and ovary adenocarcinoma cells. | 2018 Mar |
2 |
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29182407 | Metformin is associated with reduced cell proliferation in human endometrial cancer by inbibiting PI3K/AKT/mTOR signaling. | 2018 May |
4 |
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29285650 | Synergistic cytotoxicity of the dipeptidyl peptidase-IV inhibitor gemigliptin with metformin in thyroid carcinoma cells. | 2018 Feb |
1 |
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29285837 | New metformin derivative HL156A prevents oral cancer progression by inhibiting the insulin-like growth factor/AKT/mammalian target of rapamycin pathways. | 2018 Mar |
1 |
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29286158 | Metformin inhibits HaCaT cell viability via the miR-21/PTEN/Akt signaling pathway. | 2018 Mar |
2 |
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29334602 | High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy. | 2018 Oct |
1 |
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29342230 | Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells. | 2018 Feb 1 |
1 |
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29422962 | Metformin and cancer: An existing drug for cancer prevention and therapy. | 2018 Jan |
1 |
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29435022 | Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway. | 2018 Mar |
2 |
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29467552 | Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase. | 2018 Feb 21 |
1 |
| 76 |
29467947 | Metformin inhibits TGF-β1-induced epithelial-to-mesenchymal transition-like process and stem-like properties in GBM via AKT/mTOR/ZEB1 pathway. | 2018 Jan 23 |
3 |
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29552226 | The co-treatment of metformin with flavone synergistically induces apoptosis through inhibition of PI3K/AKT pathway in breast cancer cells. | 2018 Apr |
2 |
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29665787 | Valproic acid sensitizes metformin-resistant human renal cell carcinoma cells by upregulating H3 acetylation and EMT reversal. | 2018 Apr 17 |
1 |
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29678660 | Metformin combined with quercetin synergistically repressed prostate cancer cells via inhibition of VEGF/PI3K/Akt signaling pathway. | 2018 Jul 20 |
3 |
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29725482 | Metformin inhibits the proliferation and metastasis of osteosarcoma cells by suppressing the phosphorylation of Akt. | 2018 May |
1 |
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30023463 | Combination of BEZ235 and Metformin Has Synergistic Effect on Cell Viability in Colorectal Cancer Cells. | 2018 Jun |
1 |
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30032136 | Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells. | 2018 |
1 |
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30046513 | Metformin Treatment Inhibits Motility and Invasion of Glioblastoma Cancer Cells. | 2018 |
1 |
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30171812 | Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway. | 2018 Sep 1 |
1 |
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30242671 | Effects of metformin on the PI3K/AKT/FOXO1 pathway in anaplastic thyroid Cancer cell lines. | 2018 Dec |
3 |
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30259865 | Bifurcation analysis of insulin regulated mTOR signalling pathway in cancer cells. | 2018 Oct |
3 |
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30333878 | Metformin reverses the resistance mechanism of lung adenocarcinoma cells that knocks down the Nrf2 gene. | 2018 Nov |
3 |
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30378162 | Improved angiogenic activity of endothelial progenitor cell in diabetic patients treated with insulin plus metformin. | 2018 Oct 30 |
1 |
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30533337 | Three May Be Better Than Two: A Proposal for Metformin Addition to PI3K/Akt Inhibitor-antiandrogen Combination in Castration-resistant Prostate Cancer. | 2018 Oct 2 |
2 |
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27128966 | Metformin induces degradation of cyclin D1 via AMPK/GSK3β axis in ovarian cancer. | 2017 Feb |
1 |
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27857021 | Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. | 2017 Jul |
3 |
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28052008 | Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. | 2017 Jan 31 |
1 |
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28230206 | MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway. | 2017 Feb 23 |
1 |
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28338172 | Antidiabetic drug metformin mitigates ovarian cancer SKOV3 cell growth by triggering G2/M cell cycle arrest and inhibition of m-TOR/PI3K/Akt signaling pathway. | 2017 Mar |
1 |
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28525374 | The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS). | 2017 Jul 11 |
2 |
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28927780 | Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells. | 2017 Sep |
2 |
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29085821 | Screening Novel Molecular Targets of Metformin in Breast Cancer by Proteomic Approach. | 2017 |
1 |
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29241458 | Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells. | 2017 Dec 14 |
5 |
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29262637 | Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells. | 2017 Nov 28 |
1 |
| 100 |
26496641 | Metformin-Derived Growth Inhibition in Renal Cell Carcinoma Depends on miR-21-Mediated PTEN Expression. | 2016 |
1 |