Title : Mechanisms by which low glucose enhances the cytotoxicity of metformin to cancer cells both in vitro and in vivo.

Pub. Date : 2014

PMID : 25254953






1 Functional Relationships(s)
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1 Additionally, under low glucose conditions metformin significantly decreased phosphorylation of AKT and various targets of mTOR, while phospho-AMPK was not significantly altered. Metformin AKT serine/threonine kinase 1 Homo sapiens