Pub. Date : 2014 Apr
PMID : 24480115
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin modulates PI3K and GLUT4 expression and Akt/PKB phosphorylation in human endometrial stromal cells after stimulation with androgen and insulin. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Metformin modulates PI3K and GLUT4 expression and Akt/PKB phosphorylation in human endometrial stromal cells after stimulation with androgen and insulin. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | OBJECTIVE: To assess the effect of metformin on expression of Akt, ERK, PI3K and GLUT4, proteins associated with the growth factor signaling cascade, in human endometrial stromal cells after stimulation with androgen and insulin. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | The ERK protein was not affected, whereas the Akt phosphorylation was significantly decreased by the action of metformin. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | Akt phosphorylation was inhibited by metformin, possibly due to its anti-proliferative action. | Metformin | AKT serine/threonine kinase 1 | Homo sapiens |