Title : The sphingosine kinase inhibitor SKI-V suppresses cervical cancer cell growth.

Pub. Date : 2022

PMID : 35541904






1 Functional Relationships(s)
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1 Significantly, SKI-V also provoked programmed necrosis cascade in cervical cancer cells, as it induced mitochondrial p53-cyclophilin-D-adenine nucleotide translocator-1 (ANT1) complexation, mitochondrial membrane potential collapse, reactive oxygen species production and the release of lactate dehydrogenase into the medium. Reactive Oxygen Species tumor protein p53 Homo sapiens