Pub. Date : 2021 May
PMID : 33325610
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Co-administration of the ROS inhibitor NAC largely abolished the up-regulated p53 protein level, and rescued the suppressed viability and colony formation ability in butein-exposed U-2 OS cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | Taken together, our data proposed the increased ROS by butein exposure activated p53, and the activated p53 was involved in the anti-proliferative effect of butein via inducing senescence in U-2 OS cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |