Title : Dual Role of Reactive Oxygen Species and their Application in Cancer Therapy.

Pub. Date : 2021

PMID : 34405016






1 Functional Relationships(s)
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1 Interestingly, massive accumulation of ROS inhibits tumor growth in two ways: (1) by blocking cancer cell proliferation by suppressing the proliferation signaling pathway, cell cycle, and the biosynthesis of nucleotides and ATP and (2) by inducing cancer cell death via activating endoplasmic reticulum stress-, mitochondrial-, and P53- apoptotic pathways and the ferroptosis pathway. Reactive Oxygen Species tumor protein p53 Homo sapiens