Pub. Date : 2021 Dec 9
PMID : 34886886
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | CONCLUSION: Evidence indicated that the endogenous p53 status affected the sensitivity of ATC cells to EVO-induced apoptosis and G2/M arrest, revealing the potential role of p53 related to increased ROS production and disrupted MMP in the anticancer actions of EVO, and alkylation at position 14 of EVO is a critical substitution for apoptosis of ATC cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
2 | CONCLUSION: Evidence indicated that the endogenous p53 status affected the sensitivity of ATC cells to EVO-induced apoptosis and G2/M arrest, revealing the potential role of p53 related to increased ROS production and disrupted MMP in the anticancer actions of EVO, and alkylation at position 14 of EVO is a critical substitution for apoptosis of ATC cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |