Pub. Date : 2022 Mar 23
PMID : 35107378
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, the expressions of HUWE1 and TRAF6 were significantly down-regulated during WSSV (White spot syndrome virus) infection, and therefore the ubiquitination of p53 was interrupted, leading to the activation of apoptosis and ROS (Reactive oxygen species) signals through p53 accumulation, which eventually suppressed viral invasion in mud crab. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | Moreover, the expressions of HUWE1 and TRAF6 were significantly down-regulated during WSSV (White spot syndrome virus) infection, and therefore the ubiquitination of p53 was interrupted, leading to the activation of apoptosis and ROS (Reactive oxygen species) signals through p53 accumulation, which eventually suppressed viral invasion in mud crab. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 3 | Moreover, the expressions of HUWE1 and TRAF6 were significantly down-regulated during WSSV (White spot syndrome virus) infection, and therefore the ubiquitination of p53 was interrupted, leading to the activation of apoptosis and ROS (Reactive oxygen species) signals through p53 accumulation, which eventually suppressed viral invasion in mud crab. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 4 | Moreover, the expressions of HUWE1 and TRAF6 were significantly down-regulated during WSSV (White spot syndrome virus) infection, and therefore the ubiquitination of p53 was interrupted, leading to the activation of apoptosis and ROS (Reactive oxygen species) signals through p53 accumulation, which eventually suppressed viral invasion in mud crab. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 5 | Our findings revealed that p53 ubiquitination could affect ROS and apoptosis signals to cope with WSSV infection in mud crab, which firstly clarified the immunologic functions and mechanisms of p53 ubiquitination in invertebrates. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 6 | Our findings revealed that p53 ubiquitination could affect ROS and apoptosis signals to cope with WSSV infection in mud crab, which firstly clarified the immunologic functions and mechanisms of p53 ubiquitination in invertebrates. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |