Pub. Date : 2021 Jun 15
PMID : 34131139
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we identify iPLA2beta as a critical regulator for p53-driven ferroptosis upon reactive oxygen species (ROS)-induced stress. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | We found that iPLA2beta-mediated detoxification of peroxidized lipids is sufficient to suppress p53-driven ferroptosis upon ROS-induced stress, even in GPX4-null cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |