Pub. Date : 2021 Mar 25
PMID : 33181285
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antrodia camphorata extract (ACE)-induced apoptosis is associated with BMP4 expression and p53-dependent ROS generation in human colon cancer cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | We found that cell death is reversible via inactivation or knockdown of p53 gene and reduction of reactive oxygen species (ROS) generation in response to ACE exposure, indicating that p53 plays an important role in ROS generation induced by ACE. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 3 | We found that cell death is reversible via inactivation or knockdown of p53 gene and reduction of reactive oxygen species (ROS) generation in response to ACE exposure, indicating that p53 plays an important role in ROS generation induced by ACE. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 4 | We found that cell death is reversible via inactivation or knockdown of p53 gene and reduction of reactive oxygen species (ROS) generation in response to ACE exposure, indicating that p53 plays an important role in ROS generation induced by ACE. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 5 | We found that cell death is reversible via inactivation or knockdown of p53 gene and reduction of reactive oxygen species (ROS) generation in response to ACE exposure, indicating that p53 plays an important role in ROS generation induced by ACE. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 6 | CONCLUSION: Our findings demonstrate that ACE has potential as an anticancer agent that induces apoptosis through BMP4 and p53-dependent response to ROS in human colon cancer. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |