Title : Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells.

Pub. Date : 2022 Mar

PMID : 34823034






1 Functional Relationships(s)
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1 RESULTS: At 2-4 h after PDT treatment, ROS was dramatically elevated in lewis cells, DNA double-strand breaks (DDSB) occurred, as well as up-regulation of DDR proteins gamma-H2A.X, p-ATM, and p53. Reactive Oxygen Species tumor protein p53 Homo sapiens