Tyrosine

interferon gamma ; Homo sapiens







179 Article(s)
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1 35016033 Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses. 2022 Feb 3 1
2 34303919 Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK. 2021 Sep 1
3 34390807 The anti-parallel dimer binding interface in STAT3 transcription factor is required for the inactivation of cytokine-mediated signal transduction. 2021 Nov 1
4 31634391 All-trans Retinoic Acid Counteracts Diarrhea and Inhibition of Downregulated in Adenoma Expression in Gut Inflammation. 2020 Mar 4 2
5 33204297 Comprehensive Analysis of Differently Expressed and Methylated Genes in Preeclampsia. 2020 1
6 30922782 Receptor complex and signalling pathway of the two type II IFNs, IFN-γ and IFN-γrel in mandarin fish or the so-called Chinese perch Siniperca chuatsi. 2019 Aug 1
7 28736298 Calcitriol-mediated reduction in IFN-γ output in T cell large granular lymphocytic leukemia requires vitamin D receptor upregulation. 2018 Mar 2
8 29796172 Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies. 2018 May 1 2
9 30007645 Discovery of a polysaccharide from the fruiting bodies of Lepista sordida as potent inhibitors of indoleamine 2, 3-dioxygenase (IDO) in HepG2 cells via blocking of STAT1-mediated JAK-PKC-δ signaling pathways. 2018 Oct 1 1
10 28174303 Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses. 2017 Mar 17 2
11 28514139 Bioorthogonal Protein Conjugation: Application to the Development of a Highly Sensitive Bioluminescent Immunoassay for the Detection of Interferon-γ. 2017 Jun 21 1
12 25584415 Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation. 2015 Mar 1
13 25687700 Interferon-γ-induced neurotoxicity of human astrocytes. 2015 1
14 26232434 Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1. 2015 Sep 15 2
15 26275341 The two interfaces of the STAT1 N-terminus exhibit opposite functions in IFNγ-regulated gene expression. 2015 Oct 1
16 26339056 Structural Basis of the Inhibition of STAT1 Activity by Sendai Virus C Protein. 2015 Nov 2
17 24518246 An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. 2014 Sep 1
18 24838635 Signal transducer and activator of transcription 1 (STAT1) acts like an oncogene in malignant pleural mesothelioma. 2014 Jul 2
19 24847715 A conserved motif in the linker domain of STAT1 transcription factor is required for both recognition and release from high-affinity DNA-binding sites. 2014 1
20 24936834 DC-HIL-expressing myelomonocytic cells are critical promoters of melanoma growth. 2014 Nov 1
21 25340519 Trypanosoma cruzi evades the protective role of interferon-gamma-signaling in parasite-infected cells. 2014 1
22 25379383 Structural and functional characterization of salmon STAT1, STAT2 and IRF9 homologs sheds light on interferon signaling in teleosts. 2014 1
23 25526807 DNA binding reduces the dissociation rate of STAT1 dimers and impairs the interdimeric exchange of protomers. 2014 Dec 20 2
24 23582260 Evidence against a role for β-arrestin1 in STAT1 dephosphorylation and the inhibition of interferon-γ signaling. 2013 Apr 11 2
25 23804808 Human β-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells. 2013 Sep 1
26 23922848 Clinically relevant dimer interface mutants of STAT1 transcription factor exhibit differential gene expression. 2013 1
27 22253910 Identifying mechanisms by which Escherichia coli O157:H7 subverts interferon-γ mediated signal transducer and activator of transcription-1 activation. 2012 1
28 22526675 Enterohemorrhagic Escherichia coli O157:H7 Shiga toxins inhibit gamma interferon-mediated cellular activation. 2012 Jul 2
29 22595141 A novel internalization motif regulates human IFN-γ R1 endocytosis. 2012 Aug 1
30 22757586 Mathematical modelling unravels regulatory mechanisms of interferon-γ-induced STAT1 serine-phosphorylation and MUC4 expression in pancreatic cancer cells. 2012 Jun 1
31 22947424 Arachidonic acid and its COX1/2 metabolites inhibit interferon-γ mediated induction of indoleamine-2,3 dioxygenase in THP-1 cells and human monocytes. 2012 Oct-Nov 1
32 23185240 Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells. 2012 1
33 20888416 STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes. 2011 Feb 1
34 21189227 Resveratrol down-regulates interferon-γ-inducible inflammatory genes in macrophages: molecular mechanism via decreased STAT-1 activation. 2011 Oct 1
35 21303487 Importance of serine727 phosphorylated STAT1 in IFNγ-induced signaling and apoptosis of human salivary gland cells. 2011 Feb 2
36 21386060 Both type I and II IFN induce insulin resistance by inducing different isoforms of SOCS expression in 3T3-L1 adipocytes. 2011 Jun 1
37 21511030 Negative regulation of interferon-γ/STAT1 signaling through cell adhesion and cell density-dependent STAT1 dephosphorylation. 2011 Aug 1
38 21992896 Salvianolic acid B suppresses IFN-γ-induced JAK/STAT1 activation in endothelial cells. 2011 Dec 1
39 19889762 Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling. 2010 Jan 1
40 20510203 Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112. 2010 Sep 15 2
41 20643137 Molecular basis for the recognition of phosphorylated STAT1 by importin alpha5. 2010 Sep 10 1
42 21084836 STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest. 2010 Dec 1 1
43 19009233 The fungal secondary metabolite trichodimerol inhibits TGF-β dependent cellular effects and tube formation of MDA-MB-231 cells. 2009 Dec 1
44 19176616 Noncytolytic clearance of sindbis virus infection from neurons by gamma interferon is dependent on Jak/STAT signaling. 2009 Apr 1
45 19231233 Cytokine production through PKC/p38 signaling pathways, not through JAK/STAT1 pathway, in mast cells stimulated with IFNgamma. 2009 Apr 1
46 19542364 Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2. 2009 Jul 15 1
47 19635391 Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption. 2009 Jul 1
48 19846878 Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation. 2009 Nov 15 1
49 17719815 IGFBP-3 sensitizes prostate cancer cells to interferon-gamma-induced apoptosis. 2008 Feb 1
50 18566411 Activation of the JAK/STAT-1 signaling pathway by IFN-gamma can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG. 2008 Jul 1 2