Title : Discovery of a polysaccharide from the fruiting bodies of Lepista sordida as potent inhibitors of indoleamine 2, 3-dioxygenase (IDO) in HepG2 cells via blocking of STAT1-mediated JAK-PKC-δ signaling pathways.

Pub. Date : 2018 Oct 1

PMID : 30007645






1 Functional Relationships(s)
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1 Moreover, tyrosine 701 and serine 727 phosphorylation of STAT1 were dramatically reduced by LSP pretreatment in IFN-gamma-stimulated HepG2 cells. Tyrosine interferon gamma Homo sapiens