Title : Human β-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells.

Pub. Date : 2013 Sep

PMID : 23804808






1 Functional Relationships(s)
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1 The increase in PTPase activity was confirmed by demonstrating that hBD-3 suppresses IFN-gamma-induced STAT1 tyrosine phosphorylation but not STAT1 serine and ERK1/2 threonine phosphorylation and stimulates the translocation of SHP-2 into the nucleus within 15 min. Tyrosine interferon gamma Homo sapiens