Title : Arachidonic acid and its COX1/2 metabolites inhibit interferon-γ mediated induction of indoleamine-2,3 dioxygenase in THP-1 cells and human monocytes.

Pub. Date : 2012 Oct-Nov

PMID : 22947424






1 Functional Relationships(s)
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1 Further mechanistic analysis revealed that AA interfered with the transcriptional function of the IFNgamma signalling pathway by reducing phosphorylation of signal transducer and activator of transcription (STAT1) on tyrosine 701. Tyrosine interferon gamma Homo sapiens