Title : Interferon-γ-induced neurotoxicity of human astrocytes.

Pub. Date : 2015

PMID : 25687700






1 Functional Relationships(s)
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1 This interferon- gamma-induced astrocytic neurotoxicity is mediated by the activation of the Janus kinase-signal transducer and activator of transcription (STAT) 3 pathway in the astrocytes, and involves intracellular phosphorylation of STAT3 at tyrosine-705 residue. Tyrosine interferon gamma Homo sapiens