Pub. Date : 2015 Sep 15
PMID : 26232434
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Parafibromin Is a Component of IFN-gamma-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1. | Tyrosine | interferon gamma | Homo sapiens |
2 | Overexpression of parafibromin promoted IFN-gamma-triggered phosphorylation of STAT1 at Tyr(701), subsequent expression of downstream genes, and cellular antiviral response, whereas knockdown of parafibromin had opposite effects. | Tyrosine | interferon gamma | Homo sapiens |