Title : The two interfaces of the STAT1 N-terminus exhibit opposite functions in IFN╬│-regulated gene expression.

Pub. Date : 2015 Oct

PMID : 26275341






1 Functional Relationships(s)
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1 Similarly to a STAT1 mutant with impaired tetramerization, the N-terminal gain-of-function mutants showed elevated tyrosine-phosphorylation levels and prolonged nuclear accumulation upon stimulation of cells with IFNgamma. Tyrosine interferon gamma Homo sapiens