Title : Clinically relevant dimer interface mutants of STAT1 transcription factor exhibit differential gene expression.

Pub. Date : 2013

PMID : 23922848






1 Functional Relationships(s)
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1 First, we confirmed that IFNgamma-stimulation of transfected cells led to enhanced tyrosine phosphorylation of mutant STAT1 as compared to the wild-type protein, which consequently resulted in its prolonged nuclear accumulation. Tyrosine interferon gamma Homo sapiens