Title : Enterohemorrhagic Escherichia coli O157:H7 Shiga toxins inhibit gamma interferon-mediated cellular activation.

Pub. Date : 2012 Jul

PMID : 22526675






2 Functional Relationships(s)
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1 The data showed that IFN-gamma-mediated Stat-1 tyrosine phosphorylation was inhibited by EHEC secreted proteins. Tyrosine interferon gamma Homo sapiens
2 We conclude that while other factors are likely involved in the suppression of IFN-gamma-mediated Stat-1 tyrosine phosphorylation, E. coli-derived Shiga toxins represent a novel mechanism by which EHEC evades the host immune system. Tyrosine interferon gamma Homo sapiens