Guanosine Diphosphate

cell division cycle 42 ; Homo sapiens







73 Article(s)
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1 35215978 Vav Proteins in Development of the Brain: A Potential Relationship to the Pathogenesis of Congenital Zika Syndrome? 2022 Feb 14 1
2 35583642 Targeting Cancer by Using Nanoparticles to Modulate RHO GTPase Signaling. 2022 1
3 33347888 Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics. 2021 Jan 19 2
4 30714195 Dissociation mechanism of GDP from Cdc42 via DOCK9 revealed by molecular dynamics simulations. 2019 Jun 12
5 30754684 Focus on Cdc42 in Breast Cancer: New Insights, Target Therapy Development and Non-Coding RNAs. 2019 Feb 11 2
6 31330900 The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System. 2019 Jul 21 1
7 31474712 GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion. 2019 1
8 30558664 Expression of FGD4 positively correlates with the aggressive phenotype of prostate cancer. 2018 Dec 17 1
9 26542736 Guanine nucleotide induced conformational change of Cdc42 revealed by hydrogen/deuterium exchange mass spectrometry. 2016 Jan 4
10 26911374 Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression. 2016 Apr 1
11 27010858 ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells. 2016 Mar 24 1
12 27628050 Rho GTPases: Regulation and roles in cancer cell biology. 2016 Oct 2
13 24347642 A Cdc42- and Rac-interactive binding (CRIB) domain mediates functions of coronin. 2014 Jan 7 1
14 25305482 RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication. 2014 Nov 7 1
15 24067935 ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding. 2013 Nov 1
16 24100016 Activated Cdc42-bound IQGAP1 determines the cellular endocytic site. 2013 Dec 1
17 24286829 The role of Cdc42 and Gic1 in the regulation of septin filament formation and dissociation. 2013 Nov 28 1
18 22705156 WNT-3a modulates platelet function by regulating small GTPase activity. 2012 Jul 30 1
19 21549598 Development of a fluorogenic sensor for activated Cdc42. 2011 Sep 1 1
20 19890090 Small G proteins in islet beta-cell function. 2010 Feb 1
21 20028975 Differential phosphorylation of RhoGDI mediates the distinct cycling of Cdc42 and Rac1 to regulate second-phase insulin secretion. 2010 Feb 26 1
22 19221465 An atypical necrotic signal induced by immunosuppressive and anti-viral agents. 2009 Apr 1
23 19356586 Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42. 2009 Mar 27 3
24 19581296 New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes. 2009 Aug 28 5
25 19745154 Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. 2009 Sep 11 2
26 18348980 Effector proteins exert an important influence on the signaling-active state of the small GTPase Cdc42. 2008 May 16 4
27 18558478 Cellular signaling for activation of Rho GTPase Cdc42. 2008 Nov 2
28 18728185 Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway. 2008 Sep 2 1
29 17145773 Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. 2007 Feb 1
30 16337026 AlphaPIX and betaPIX and their role in focal adhesion formation. 2006 Apr 1
31 16489751 Solution structure of an oncogenic mutant of Cdc42Hs. 2006 Feb 28 9
32 16998826 Rho GTPase activity zones and transient contractile arrays. 2006 Oct 1
33 15649357 The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade. 2005 Jan 11 1
34 16101281 Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK). 2005 Aug 23 1
35 16190977 RhoGDIs revisited: novel roles in Rho regulation. 2005 Nov 1
36 16201754 A Cdc42 mutant specifically activated by intersectin. 2005 Oct 11 1
37 14973186 Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled gamma-phosphate-linked GTP analogs. 2004 Mar 2 1
38 15287724 Backbone dynamics of an oncogenic mutant of Cdc42Hs shows increased flexibility at the nucleotide-binding site. 2004 Aug 10 2
39 15530857 An activating mutant of Cdc42 that fails to interact with Rho GDP-dissociation inhibitor localizes to the plasma membrane and mediates actin reorganization. 2004 Dec 10 1
40 12760905 Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion. 2003 Sep 1
41 11883956 Probing the binding states of GDP to Cdc42 using urea interaction. 2002 Mar 15 5
42 11948177 IQGAP1 is a component of Cdc42 signaling to the cytoskeleton. 2002 Jul 5 2
43 11952837 Association of frabin with specific actin and membrane structures. 2002 Apr 1
44 12369824 Antiapoptotic Cdc42 mutants are potent activators of cellular transformation. 2002 Oct 15 4
45 12432077 Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. 2002 Dec 15 1
46 12501193 Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis. 2002 Dec 31 2
47 11285260 Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP. 2001 Jun 15 5
48 11294626 An increase in side chain entropy facilitates effector binding: NMR characterization of the side chain methyl group dynamics in Cdc42Hs. 2001 Apr 17 1
49 11583574 RhoGDI-binding-defective mutant of Cdc42Hs targets to membranes and activates filopodia formation but does not cycle with the cytosol of mammalian cells. 2001 Oct 15 1
50 10676816 Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. 2000 Feb 4 1