Title : The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.

Pub. Date : 2005 Jan 11

PMID : 15649357






1 Functional Relationships(s)
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1 RESULTS: We show that the binding of activated Cdc42 to the Cool-2 dimer markedly enhances its ability to associate with GDP bound Rac1, resulting in a significant activation of Rac-GEF activity. Guanosine Diphosphate cell division cycle 42 Homo sapiens