Abiraterone Acetate

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







97 Article(s)
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51 25295126 A multicentre analysis of abiraterone acetate in Canadian patients with metastatic castration-resistant prostate cancer. 2014 Sep 1
52 25361624 Use of prednisone with abiraterone acetate in metastatic castration-resistant prostate cancer. 2014 Dec 1
53 25374921 PI-3 kinase p110β: a therapeutic target in advanced prostate cancers. 2014 1
54 22552048 Efficacy of docetaxel-based chemotherapy following ketoconazole in metastatic castration-resistant prostate cancer: implications for prior therapy in clinical trials. 2013 Nov 1
55 23319868 Clinical appraisal of abiraterone in the treatment of metastatic prostatic cancer: patient considerations, novel opportunities, and future directions. 2013 1
56 23371447 Targeting the adrenal gland in castration-resistant prostate cancer: a case for orteronel, a selective CYP-17 17,20-lyase inhibitor. 2013 Apr 1
57 23898269 Metastatic castration-resistant prostate cancer: two case reports of dramatic response with abiraterone acetate in patients heavily pretreated with chemotherapy. 2013 May 1
58 24271422 Abiraterone acetate: a review of its use in patients with metastatic castration-resistant prostate cancer. 2013 Dec 2
59 24314737 [Prostate cancer and new hormonal treatments: mechanism of action and main clinical results]. 2013 Oct 1
60 24314739 [CYP17A1 inhibitors in prostate cancer: mechanisms of action independent of the androgenic pathway]. 2013 Oct 1
61 24482578 Clinical Evaluation of Abiraterone in the Treatment of Metastatic Prostate Cancer. 2013 Jul 10 1
62 21986558 Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer. 2012 Sep 5 1
63 22064602 The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer. 2012 Feb 1
64 22149426 Abiraterone acetate, a first-in-class CYP17 inhibitor, establishes a new treatment paradigm in castration-resistant prostate cancer. 2012 Jan 1
65 22170708 Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer. 2012 Feb 4
66 22198164 Abiraterone acetate: redefining hormone treatment for advanced prostate cancer. 2012 Mar 1
67 22222232 Human steroid biosynthesis for the oncologist. 2012 Feb 1
68 22291466 Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer. 2012 2
69 22327837 The evolving paradigm of second-line hormonal therapy options for castration-resistant prostate cancer. 2012 May 1
70 22373838 Therapeutic options for advanced prostate cancer: 2011 update. 2012 Apr 1
71 22430753 [Abiraterone acetate: a novel therapeutic option in hormone-refractory prostate cancer]. 2012 Feb 2
72 22451619 Abiraterone in prostate cancer: a new angle to an old problem. 2012 Apr 1 2
73 22825325 Medical strategies for treatment of castration resistant prostate cancer (CRPC) docetaxel resistant. 2012 Sep 1
74 23355790 Targeting the androgen receptor in the management of castration-resistant prostate cancer: rationale, progress, and future directions. 2012 Dec 1
75 23795335 Abiraterone for the Treatment of Advanced Prostate Cancer. 2012 Sep 1 2
76 21243537 Abiraterone acetate, a novel adrenal inhibitor in metastatic castration-resistant prostate cancer. 2011 Apr 1
77 21372223 New strategies in metastatic prostate cancer: targeting the androgen receptor signaling pathway. 2011 Apr 1 1
78 21455038 Contemporary management of metastatic castration-resistant prostate cancer. 2011 May 1
79 21860772 Limited expression of cytochrome p450 17α-hydroxylase/17,20-lyase in prostate cancer cell lines. 2011 Jul 1
80 21985170 Abiraterone acetate: in metastatic castration-resistant prostate cancer. 2011 Oct 22 1
81 20159814 Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. 2010 Mar 20 1
82 20159823 Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. 2010 Mar 20 2
83 20159824 Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. 2010 Mar 20 2
84 20225998 Abiraterone acetate for castration resistant prostate cancer. 2010 Apr 2
85 20465382 Abiraterone acetate: a promising drug for the treatment of castration-resistant prostate cancer. 2010 May 2
86 20524793 New agents and strategies for the hormonal treatment of castration-resistant prostate cancer. 2010 Jul 1
87 20645691 Efficacy of abiraterone acetate in post-docetaxel castration-resistant prostate cancer. 2010 Jul 2
88 18957947 Is abiraterone acetate well tolerated and effective in the treatment of castration-resistant prostate cancer? 2009 Jan 1
89 19223900 CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer. 2009 Mar 10 1
90 19470933 Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. 2009 Aug 10 3
91 19509232 Antitumor activity with CYP17 blockade indicates that castration-resistant prostate cancer frequently remains hormone driven. 2009 Jun 15 2
92 19719456 Hormonal therapy for prostate cancer: toward further unraveling of androgen receptor function. 2009 Dec 1
93 19995520 Words of wisdom. Re: Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. Attard G, Reid AH, Yap TA, et al. J Clin Oncol 2008;26:4563-71. 2009 Jul 1
94 19995526 Words of wisdom. Re: Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. 2009 Oct 1
95 20050017 Words of wisdom. Re: Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. Attard G, Reide AHM, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper C, Kaye S, Dearnaley D, Lee G, de Bono JS. J Clin Oncol 2008;26:4563-71. 2009 Jan 1
96 18645193 Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. 2008 Oct 1 4
97 19189435 Words of wisdom. Re: phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration- resistant prostate cancer commonly remains hormone driven. 2008 Dec 1