Title : CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer.

Pub. Date : 2009 Mar 10

PMID : 19223900






1 Functional Relationships(s)
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1 The novel, orally available, small-molecule compound, abiraterone acetate, is undergoing evaluation in early clinical trials and emerging data have shown that the selective, irreversible and continuous inhibition of CYP17 is safe with durable responses in CRPC. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens