Title : Targeting the androgen receptor in the management of castration-resistant prostate cancer: rationale, progress, and future directions.

Pub. Date : 2012 Dec

PMID : 23355790






1 Functional Relationships(s)
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1 Two new drugs-the CYP17 inhibitor abiraterone acetate and the potent ar antagonist enzalutamide-were recently shown to prolong overall survival after chemotherapy treatment in patients with metastatic disease, with the former agent also demonstrating impressive activity in the pre-chemotherapy setting. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens