Title : Clinical appraisal of abiraterone in the treatment of metastatic prostatic cancer: patient considerations, novel opportunities, and future directions.

Pub. Date : 2013

PMID : 23319868






1 Functional Relationships(s)
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1 Abiraterone acetate is a selective, irreversible inhibitor of CYP17 and can suppress adrenal synthesis of androgen precursors, and possibly in situ steroidogenesis in the tumor microenvironment. Abiraterone Acetate cytochrome P450 family 17 subfamily A member 1 Homo sapiens